May 28, 2006

Joseph Leondis

Trustee

Foster Foundation

25 Rockaway Avenue

Garden City, NY 11530

(516) 746-3343

Dear Mr. Leondis:

Once again I am expressing my sincere thanks to you and the Foster Foundation for both your

direct support and advocacy for our shared vision and mission of using research to improve the care and

lives of patients afflicted with osteosarcoma. With your support I believe we are making a difference and

we will continue to do so. I look forward to sharing our results with you and the Foundation. I am hopeful

that trials of signal transduction inhibitors in osteosarcoma will be initiated and demonstrate efficacy.

Thank you and the Foster Foundation for supporting our laboratories efforts. Your support has

made the important work that we do possible.

Sincerely,

Richard Gorlick, MD

Associate Professor of Pediatrics and Molecular Pharmacology

Albert Einstein College of Medicine

Vice Chairman, Division Chief of Hematology/Oncology

Department of Pediatrics

The Children's Hospital at Montefiore

3415 Bainbridge Avenue, Rosenthal 3rd Floor

Bronx, New York 10467

Section # - 718 - 741-2342, Fax # - 718 - 920-6506